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No excess mortality seen in contemporary undifferentiated arthritis
Patients who meet the contemporary criteria for undifferentiated arthritis do not appear to have an increase in excess mortality, unlike those who...
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Fewer diabetes complications with NOACs in patients with AFib
Taking non–vitamin K oral anticoagulants is associated with lower mortality and fewer diabetes complications vs. taking warfarin in patients with...
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Allopurinol found safe in patients with concomitant gout, CKD
Despite earlier concerns, a study has found no sign of increased mortality with allopurinol therapy in patients with gout and chronic kidney...
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Cardiac function normalizes by 3 months in MIS-C in study
Children with COVID-19–related multisystem inflammatory syndrome show normalization of cardiac function by 3 months after diagnosis.
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AI holds its own against pathologists for prostate cancer diagnosis
Deep learning algorithms have shown a high level of agreement with expert uropathologists in diagnosing and grading prostate cancer.
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Delays in cancer referral, diagnosis linked with morbidities
Patients with multiple morbidities were much more likely to have their cancer diagnosed at least 60 days after initial primary care consultation...
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Platelet-rich plasma injections show no benefit in knee OA in placebo-controlled trial
Platelet-rich plasma injections for mild to moderate knee osteoarthritis show no improvements in pain, function, or cartilage structure, compared...
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High tibial osteotomy achieves sustained improvements in knee OA
Medial opening wedge high tibial osteotomy is associated with improvements in pain and function in knee osteoarthritis.
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Which comes first in osteoarthritis: The damage or the pain?
Osteoarthritis experts debate whether pain is the result of joint damage or a cause of it.
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Stable, supportive shoes reduce walking pain in severe knee OA
Stable, supportive footwear achieved greater reductions in knee osteoarthritis pain than did flat, flexible shoes.
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Insoles or braces show best pain relief for knee OA
Meta-analysis finds low-quality evidence for biochemical interventions but favors combination insoles or braces for knee OA.
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Intramuscular glucocorticoid injections seen as noninferior to intra-articular in knee OA
Intramuscular injections of glucocorticoids achieve a level of pain reduction similar to that of intra-articular injections in patients with knee...
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Weight cycling linked to cartilage degeneration in knee OA
Patterns of significant weight loss and gain are associated with more cartilage and bone marrow edema degeneration in patients with knee...
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Renal, cardiovascular damage may develop in mild SLE despite treatment
An increase in disease activity in systemic lupus erythematosus is associated with significant increases in the risk of renal and cardiovascular...
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Outcomes have improved for PAH in connective tissue disease
Modern treatments and combination approaches may have contributed to overall improvements in survival in patients with pulmonary arterial...