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Microbleeds, age contribute to ARIA risk with aducanumab
New safety results show that brain bleeds at baseline increase risk of brain edema, and that age contributes to risk of bleeds during treatment....
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Headache seen affecting some pregnancy outcomes
A new study links migraine – and also tension-type headache – to small-for-gestational-age babies.
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Novel gene therapy ‘reprograms’ cells to reverse neurologic deficits in children with rare disease
Months after surgery to deliver a gene therapy, children saw complete resolution of oculogyric crises, a hallmark of their disease, and were able...
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Two case reports identify Guillain-Barré variants after SARS-CoV-2 vaccination
Investigators in India and the United Kingdom describe rare presentations of Guillain-Barré syndrome marked by facial paralysis, but evidence of...
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The aducanumab revolution
As the controversial new Alzheimer’s drug makes its way from research settings to the clinic, practitioners brace for a potential sea change in...
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Basal ganglia microcircuits offer clues to Parkinson’s symptoms
In a mouse model of Parkinson’s disease, specific neuronal subpopulations, or microcircuits, in the basal ganglia could be manipulated to...
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Palliative care for patients with dementia: When to refer?
A systematic literature review finds few consistent criteria for referrals save for disease stage. Researchers argue that patients’ needs may be...
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Neurologic disorders ubiquitous and rising in the U.S.
Most of the rise in disease burden could be attributed to population aging, while age-standardized figures showed stroke and dementias to be level...
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Cognitive effects seen as transient for Alzheimer’s drug atabecestat
Follow-up data from a canceled trial showed that cognitive worsening from the BACE inhibitor was reversed within 6 months of stopping treatment....
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Is the EDSS an adequate outcome measure in secondary progressive MS trials?
Investigators say it may be time to replace as a primary outcome measure an instrument that registers more improvement than is likely possible in...
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Half of women treated for gynecologic cancers miss or skip doses of oral drugs
Those who did not take all their medications cited anxiety or expressed doubt about the efficacy of their regimens.
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Nebulized surfactant shows promise in large cohort
An aerosolized surfactant reduced the need for liquid surfactant treatment by half among premature infants with early mild to moderate respiratory...
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New case suggestive of in utero SARS-CoV-2 transmission
In this rare case of transmission of SARS-CoV-2 from a mother to her neonate, virus was detected in cord blood but not placenta.
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Chinese American families suffer discrimination related to COVID-19
In a sample of Chinese American parents and children, reports of racial discrimination during the pandemic were common.
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Artificially sweetened drinks add to CVD risk
People who reported consuming around 180 mL per day of beverages high in sugar or artificially sweetened drinks saw a higher risk of developing...