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Mark S. Lesney, PhD

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Sepsis transition program may lower mortality in patients discharged to post-acute care

Author:
Mark S. Lesney, PhD
Publish date: October 17, 2022

Sepsis survivors discharged to post-acute care facilities are at high risk.

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News

New ILD, asthma, and COPD trials

Author:
Mark S. Lesney, PhD
Publish date: August 9, 2022

Three new and still-recruiting trials of interest to pulmonologists and their patients are presented in this debut presentation of Clinical Trials...

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News

Sleep, not smoke, the key to COPD exacerbations?

Author:
Mark S. Lesney, PhD
Publish date: June 15, 2022

Individuals who self-reported having poor-quality sleep had a 25%-95% higher risk of COPD exacerbations.

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News

NIAID trial to test asthma drug in disadvantaged urban children

Author:
Mark S. Lesney, PhD
Publish date: June 3, 2022

“We need to find out how well approved asthma drugs work for disadvantaged children of color living in urban areas.”

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News

COPD screening for asymptomatic adults? USPSTF weighs in, again

Author:
Mark S. Lesney, PhD
Publish date: May 10, 2022

To update its 2016 recommendation, the U.S. Preventive Services Task Force commissioned a reaffirmation evidence...

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News

FDA approves generic Symbicort for asthma, COPD

Author:
Mark S. Lesney, PhD
Publish date: March 16, 2022

The approval was given for a metered-dose inhaler that contains both budesonide and formoterol.

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News

FDA approves tezepelumab-ekko (Tezspire) for severe asthma

Author:
Mark S. Lesney, PhD
Publish date: December 20, 2021

“Tezspire represents a much-needed new treatment for the many patients who remain underserved and continue to struggle with severe, uncontrolled...

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News

No added risk of hepatic cancer in patients with hemophilia after successful HCV treatment

Author:
Mark S. Lesney, PhD
Publish date: October 5, 2021

“Careful observation is needed in patients with hemophilia even after eradication of HCV.”

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News

Intracranial hemorrhaging a high risk for patients with hemophilia, especially neonates

Author:
Mark S. Lesney, PhD
Publish date: September 28, 2021

The observed rates of intracranial hemorrhaging (ICH) in patients with hemophilia were higher compared to the...

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News

Methylation patterns correlate with prognosis in children with T-ALL

Author:
Mark S. Lesney, PhD
Publish date: September 23, 2021

Hypomethylation of the asparagine synthase gene was significantly associated with poor therapeutic outcome in children with T-cell acute...

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News

Transfusions, readmissions higher for patients with CLL after cardiac surgery

Author:
Mark S. Lesney, PhD
Publish date: September 20, 2021

Most other outcomes were similar for patients with and without CLL, including mortality and infection.

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News

Can reversing T-cell exhaustion benefit in B-cell lymphoma relapse?

Author:
Mark S. Lesney, PhD
Publish date: September 15, 2021

Overall, 3 of the 12 patients showed a response after pembrolizumab: One complete response; two partial...

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News

Genetic shift increases susceptibility to childhood ALL

Author:
Mark S. Lesney, PhD
Publish date: September 9, 2021

A genetically induced shift toward higher lymphocyte counts was found to increase susceptibility to childhood...

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News

New gene variant found for hereditary bleeding disorder

Author:
Mark S. Lesney, PhD
Publish date: September 8, 2021

Reduced expression of thrombomodulin caused by the gene variant may be responsible for the disseminated...

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News

New treatments have transformed Ph+ acute lymphoblastic leukemia care

Author:
Mark S. Lesney, PhD
Publish date: August 26, 2021

BCR-ABL mutation tyrosine kinase inhibitors have transformed Ph+ ALL from an historically poor prognosis disease...

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