News
Trial halted for bleeding reduction with abelacimab vs. rivaroxaban in AFib
- Author:
- Sue Hughes
“ZALEA-TIMI 71 represents a landmark study confirming the promise of Factor XI inhibition as causing substantially less bleeding than a current...
News
SGLT2 inhibitors: No benefit or harm in hospitalized COVID-19
- Author:
- Sue Hughes
“I think the most important take-home message here is that the use of these medications appears to be safe even in really acutely ill hospitalized...
News
New ESC ACS guideline combines STEMI and NSTE-ACS
- Author:
- Sue Hughes
“After the initial triage and management decisions, then most of the rest of the care follows a common pathway so it would make sense to consider...
News
No benefit of anti-inflammatory strategy in acute myocarditis
- Author:
- Sue Hughes
Interleukin-1 receptor antagonist anakinra appeared safe but did not reduce complications of acute myocarditis in the ARAMIS trial.
News
Aspirin still needed in first month after PCI: STOPDAPT-3
- Author:
- Sue Hughes
“While these absolute event rates are extremely low, they are unquestionably higher in the nonaspirin group.”
News
Dietary nitrates reduce contrast-induced nephropathy in ACS
- Author:
- Sue Hughes
“Currently, aside from intravenous hydration, there is no proven treatment that reduces contrast-induced nephropathy. We feel that dietary...
News

IV iron shows only modest benefit in HF: HEART-FID
- Author:
- Sue Hughes
It was hoped that the study would confirm benefits suggested in previous smaller studies, but its modest results seem to have caused more...
News
Anticoagulation no benefit in presumed AFib detected by cardiac devices
- Author:
- Sue Hughes
“Based on the result of this trial, these occasional atrial high-rate episodes do not appear to be associated with stroke. It appears quite benign...
News
Acoramidis shows encouraging results in ATTR cardiomyopathy
- Author:
- Sue Hughes
“ATTRibute-CM was a robustly positive trial, showing benefits across the board for acoramidis, and suggest the tantalizing possibility of genuine...
News
New ESH hypertension guidelines aim for simplified message
- Author:
- Sue Hughes
A new feature of the guidelines is the upgrading of beta-blockers in the treatment algorithms.
News

‘Striking’ benefit of lipid lowering in primary prevention
- Author:
- Sue Hughes
“If patients can’t tolerate a statin, then treat them with bempedoic acid. The bottom line is that these patients just need to be treated.”
News
Low-dose colchicine approved for CVD: Now what?
- Author:
- Sue Hughes
“If we think patients are still at high risk of recurrent cardiovascular events, we have to think what we will do next. This is where this drug...
News

FDA OKs low-dose colchicine for broad CV indication
- Author:
- Sue Hughes
“The FDA approval of colchicine for patients with atherosclerotic disease is a huge signal that physicians need to be aware of inflammation as a...
News
Upping CO2 does not benefit OHCA patients: TAME
- Author:
- Sue Hughes
“These out-of-hospital cardiac arrest patients are a very diverse group, and it may be possible that some patients could have benefited from...
News
Support for minimally invasive mitral valve repair: Mini Mitral published
- Author:
- Sue Hughes
“Mini-thoracotomy may appeal to patients because the procedure is less disfiguring than sternotomy. The early (6-week) benefit, albeit small and...