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Sedentary postmenopausal women have higher heart failure risk

Key clinical point: More time spent sitting or lying down was associated with significantly increased risk of heart failure in older women.

Major finding: The hazard ratio for heart failure increased as study participants spent more time sitting down; for women in the most active tertile the HR was 1.00 versus 1.42 for women in the least active tertile.

Study details: The data come from 80,982 women aged 50-79 years enrolled in the Women’s Health Initiative Observational Study with no known heart failure at baseline.

Disclosures: The study was supported by the National Heart, Lung, and Blood Institute. The researchers had no financial conflicts to disclose.


LaMonte MJ et al. Circ Heart Fail. 2020 Nov 24. doi: 10.1161/CIRCHEARTFAILURE.120.007508.