Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Survival at ‘overweight’ BMI surpasses ‘normal’

Key clinical point: The optimal body mass index for survival in middle-aged adults is 25-29 kg/m2.

Major finding: People with a body mass index of 25-29 kg/m2 had significantly better survival than people with an index of 20-24 kg/m2.

Study details: PURE, a multinational, prospective, observational study that, for this analysis, included data from 142,410 people.

Disclosures: The PURE study has received partial funding from unrestricted grants from several drug companies. Dr. Leong has been an advisor to Ferring Pharmaceuticals and has been a speaker on behalf of Janssen.


Leong D. ESC 2019, Late-Breaking Science in Prevention 1