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Invasive GBS Infections in Nonpregnant US Adults

JAMA Intern Med; ePub 2019 Feb 18; Francois Watkins, et al

Among nonpregnant US adults, the incidence of invasive group B Streptococcus (GBS) is substantial and continues to increase, with chronic disease such as obesity and diabetes possibly contributing. This according to a population-based surveillance study that sought to update trends of invasive GBS disease among US adults . Primary outcomes included trends in GBS cases overall and by demographic characteristics, underlying clinical conditions of patients, and isolate characteristics. Researchers found:

  • 21,250 patients with invasive GBS among nonpregnant adults from 2008 through 2016 were detected.
  • Invasive GBS incidence among nonpregnant adults increased significantly from 8.1 cases per 100,000 population in 2008 to 10.9 in 2016.
  • Incidence was highest among those with male sex, age ≥65 years, and black race.
  • Cases had high rates of obesity (54%) and diabetes (53.4%).


Francois Watkins LK, McGee L, Schrag SJ, et al. Epidemiology of invasive Group B Streptococcal infections among nonpregnant adults in the United States, 2008-2016. [Published online ahead of print February 18, 2019]. JAMA Intern Med. doi:10.1001/jamainternmed.2018.7269.