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References

1. Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12-49. doi: 10.3322/caac.21820. 

2. Riviere P, Morgan KM, Deshler LN, et al. Racial disparities in colorectal cancer outcomes and access to care: a multi-cohort analysis. Front Public Health. 2024;12:1414361. doi:10.3389/fpubh.2024.1414361

3. Imperiale TF, Myers LJ, Barker BC, Stump TE, Daggy JK. Colon Age: A metric for whether and how to screen male veterans for early-onset colorectal cancer. Cancer Prev Res. 2024:17:377-384.  doi:10.1158/1940-6207.CAPR-23-0544

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References

1. Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12-49. doi: 10.3322/caac.21820. 

2. Riviere P, Morgan KM, Deshler LN, et al. Racial disparities in colorectal cancer outcomes and access to care: a multi-cohort analysis. Front Public Health. 2024;12:1414361. doi:10.3389/fpubh.2024.1414361

3. Imperiale TF, Myers LJ, Barker BC, Stump TE, Daggy JK. Colon Age: A metric for whether and how to screen male veterans for early-onset colorectal cancer. Cancer Prev Res. 2024:17:377-384.  doi:10.1158/1940-6207.CAPR-23-0544

References

1. Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12-49. doi: 10.3322/caac.21820. 

2. Riviere P, Morgan KM, Deshler LN, et al. Racial disparities in colorectal cancer outcomes and access to care: a multi-cohort analysis. Front Public Health. 2024;12:1414361. doi:10.3389/fpubh.2024.1414361

3. Imperiale TF, Myers LJ, Barker BC, Stump TE, Daggy JK. Colon Age: A metric for whether and how to screen male veterans for early-onset colorectal cancer. Cancer Prev Res. 2024:17:377-384.  doi:10.1158/1940-6207.CAPR-23-0544

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Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States, with an estimated 53,010 deaths and 152,810 new diagnoses in 2024.

Incidence of CRC is higher in Black patients than in White patients, and racial disparities in survival persist in the general population1 until individuals reach Medicare eligibility.2 Interestingly, data published in 2024 have shown that this trend does not appear in the VHA system, indicating that access to care may play a more crucial role than racial contributions in influencing outcomes among non-Hispanic Black and White individuals.2

CRC rates and deaths are steadily decreasing among those aged 50 years or older but are rising in individuals under age 50. Early-onset colorectal cancer (EOCRC)—cases diagnosed before age 50—now represent 10% to 11% of all CRC. Of these cases, 75% occur in people aged 40 to 49, whereas about 50% affect individuals younger than 45. A novel measure, “colon age,” quantifies EOCRC risk by taking biological factors into account. This metric can help VHA providers clarify CRC risk and help patients better grasp their screening options before age 45 or 50.3
 

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