Dermpath Diagnosis

Superficial Plantar Fibromatosis

Plantar fibromatosis typically presents as firm plaques or nodules on the plantar surface of the foot. The process is caused by a proliferation of fibroblasts and collagen and has been associated with trauma, liver disease, diabetes mellitus, epilepsy, and alcoholism. Unlike the fibromatoses associated with Gardner syndrome, superficial plantar fibromatosis has not been associated with abnormalities in the adenomatous polyposis coli gene or with the ß-catenin gene. Lesions typically present in middle-aged or elderly individuals and involve the medial plantar fascia.


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