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Thyroid disease and active smoking are prognostic factors for more severe HS

Key clinical point: Thyroid disease and active smoking may be associated with more severe hidradenitis suppurativa (HS).

Major finding: Multivariable analysis demonstrated that active smoking and thyroid disease were associated with a higher stage of HS based on the Hurley classification (odds ratio [OR], 1.38; 95% confidence interval [CI], 1.11-1.65 and OR, 1.30; 95% CI, 1.09-1.76, respectively) and IHS4 score system (OR, 1.23; 95% CI, 1.09-1.64 and OR, 1.42; 95% CI, 1.19-1.66, respectively).

Study details: The data come from a prospective cross-sectional single-center study of 290 patients with HS (mean age, 37.3 years; 51.1% females).

Disclosures: No study sponsor was identified. The authors declared no conflicts of interest.


Liakou AI et al. Dermatology. 2020 Sep 23. doi: 10.1159/000508528.