Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

E-cigarette use tied to increased COPD, asthma risk

Key clinical point: Evidence continues to accumulate linking e-cigarettes to a range of lung diseases.

Major finding: The researchers found an increased risk of respiratory disease among former e-cigarette users (incidence rate ratio, 1.28) and current e-cigarette users (IRR, 1.31).

Study details: The current analysis included data from 21,618 U.S. adults who were surveyed in four waves of the Population Assessment of Tobacco and Health study between 2013 and 2018.

Disclosures: Dr. Xie reported having no financial disclosures. His coauthors reported having received research grants and personal fees from a variety of sources.


Xie W et al. JAMA Netw Open. 2020 Nov 12. doi: 10.1001/jamanetworkopen.2020.20816