Higher consumption of dietary cholesterol or eggs is significantly associated with higher risk of incident cardiovascular disease (CVD) and all-cause mortality in a dose-response manner among US adults. Individual participant data were pooled from 6 prospective US cohorts in measuring dietary cholesterol (mg/day) or egg consumption (number/day). Researchers found:
- 29,615 adults pooled from the 6 cohort studies with a median follow-up of 17.5 years were included.
- Each additional 300 mg of dietary cholesterol consumed per day was significantly associated with a higher risk of incident CVD and all-cause mortality.
- Each additional half an egg consumed per day was significantly associated with higher risk of incident CVD and all-cause mortality.
Zhong VW, Van Horn L, Cornelis MC, et al. Associations of dietary cholesterol or egg consumption with incident cardiovascular disease and mortality. JAMA. 2019;321(11):1081–1095. doi:10.1001/jama.2019.1572.