Patients with hematologic malignancies who have influenza are prone to serious complications, particularly if they are immunosuppressed, according to a retrospective analysis involving 190 individuals. Participants were a median 49 years of age, had a hematologic malignancy, and were diagnosed with influenza between 2009 to 2014 at 1 of 2 centers. Among the results:
- Patients with leukemia, decreased albumin level, hypoxia at diagnosis, respiratory co-infection, and corticosteroid use were significantly more likely to experience lower respiratory tract infection.
- Elevated creatinine level, hypoxia at diagnosis, and respiratory co-infection, were significantly linked with 60-day mortality.
The authors noted that patients with respiratory symptoms should receive care right away during flu season.
Vilar-Compte D, Shah D, Vanichanan J, et al. Influenza in patients with hematological malignancies: Experience at two comprehensive cancer centers. [Published online ahead of print August 29, 2017]. J Med Virol. doi:10.1002/jmv.24930.
This Week's Must Reads
Must Reads in Hematologic Malignancies
Long-term ibrutinib data in older patients, Barr PM et al. Haematologica. 2018;103(9):1502-10
Prognostic Score System for Patients with PMF, J Clin Oncol; ePub 2017 Dec 9; Gugliemelli, et al
These Patients Are More Apt to Be Depressed, Ann Hematol; ePub 2017 Dec 7; Shreders, et al
Survival Length Shortest in These Patients with MF, Eur J Haematol; ePub 2017 Dec 11; Masarova, et al
The Value of Ruxolitinib Before and After AlloSCT, Blood; ePub 2017 Dec 7; Poulose, Malysz, et al