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Virtual microscopy holds its own for prostate cancer histopathology

Key clinical point: Virtual microscopy was noninferior to standard light microscopy for the histopathological evaluation of prostate cancer.

Major finding: The agreement for Gleason grading score characteristics for primary and secondary patterns were similar with both methods, and virtual microscopy showed narrower limits of agreement than light microscopy, which suggests better repeatability.

Study details: The data come from a review by two uropathologists of 413 cores on 352 slides from 60 men with prostate cancer.

Disclosures: The study was supported by the Swedish Prostate Cancer Federation and the Swedish Cancer Society. The researchers had no financial conflicts to disclose.


Zelic R et al. Sci Rep. 2021 Feb 5. doi: 10.1038/s41598-021-82911-z.