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Pregnancy History and Risk of Miscarriage

BMJ; ePub 2019 Mar 20; Magnus, et al

The risk of miscarriage varies greatly with maternal age and is increased after some adverse pregnancy outcomes, a recent study found. The prospective register-based study used logistic regression to estimate the risk of miscarriage according to a woman’s age and pregnancy history. Researchers found:

  • There were 421,201 pregnancies during the study period.
  • The risk of miscarriage was lowest in women aged 25-29 years, and rose rapidly after age 30, reaching 53% in women aged ≥45 years.
  • There was a strong recurrence risk of miscarriage.
  • The risk of miscarriage was increased if the previous pregnancy ended in a preterm delivery, caesarean section, or if the woman had gestational diabetes.


Magnus MC, Wilcox AJ, Morken N-H, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: Prospective register based study. [Published online ahead of print March 20, 2019]. BMJ. doi:10.1136/bmj.l869.