Neurology
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How does lecanemab work in Alzheimer’s?
“In our study, we looked at lecanemab and found it can block the activation of the contact system, which could be one of the reasons that it works...
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Lead exposure still a global health burden
Estimates place lead exposure on a par with ambient particulate matter and household air pollution combined, and ahead of unsafe household...
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Sedentary lifestyle tied to increased dementia risk
Dementia risk was elevated whether participants were sedentary for 10 uninterrupted hours or multiple sedentary periods that totaled 10 hours over...
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Abdominal fat linked to lower brain volume in midlife
“Overall, we found that both subcutaneous and visceral fat has similar levels of negative relationships with brain volumes.”
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Probiotics improve nonmotor symptoms of Parkinson’s
Participants taking the probiotic also saw a reduced delay in “time to on” of treatment with levodopa, thus reducing the delay until effectiveness...
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CTE common among young athletes in largest brain donor study
“A lot of people think CTE is a result of high-level, professional play such as football, ice hockey, and boxing, but it can affect amateur...
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Could retinal changes be a harbinger of Parkinson’s?
“I think we are still several years away from converting these findings into individual level prediction for patients.”
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FDA okays first biosimilar for multiple sclerosis
“Biosimilar medications offer additional effective treatment options that have the potential to increase access for people living with relapsing...
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Gene therapy offers new way to fight alcohol use disorder
Compared to primates that received a placebo intravenously, those that received the growth factor gene decreased their drinking by about 90%. They...
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Dementia diagnosis a good time to reduce polypharmacy
Time of diagnosis can be a potential inflexion point for deprescribing long-term medications with safety risks, limited benefit, or possible...