Gastrointestinal Cancer
News
Metformin May Lower Pancreatic Cancer Risk in Women
Major Finding: Overall, metformin use was not found to be associated with pancreatic cancer in 2,763 patients with a first-time diagnosis,...
News
Regorafenib Prolongs Survival After Colorectal Cancer Therapies Fail
Major Finding: Regorafenib improved overall survival (6.4 vs. 5.0 months), progression-free survival (1.9 vs. 1.7 months), and the disease control...
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Brivanib Disappoints in KRAS Wild-Type Colorectal Cancer
Major Finding: There was no significant gain in median overall survival with brivanib-cetuximab, compared with placebo-cetuximab in intention-to-...
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Gastric Cancer Subtype May Affect Bevacizumab Benefit
Major Finding: The addition of bevacizumab improved overall survival only in patients from Europe and the Americas who had diffuse or distal...
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NICE Nixes Bevacizumab, Cetuximab, and Panitumumab in Colorectal Cancer
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No Panitumumab Benefit Seen in Colorectal Cancer with KRAS Mutations
Major Finding: There were no consistent associations across trials between the most common codon 12 and 13 KRAS mutant alleles and progression-...
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Regorafenib Anticipated to Show Survival Advantage in Colorectal Cancer
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Old Antivirals Rival New for Cancer Prevention in Hepatitis B
Major Finding: The rate of hepatocellular carcinoma was 0.013-0.017 per person-year of follow-up with lamivudine, 0.015 with adefovir with or...
News
Smoking Doubles Cancer Risk in Barrett's Esophagus
Major Finding: After adjustment for demographics, presence of low-grade dysplasia, reflux symptoms, and Barrett’s segment length at diagnosis,...
News
Therapies Can Extend Life in Infiltrative Liver Cancer
Major Finding: Transcatheter arterial chemoembolization/ radiofrequency ablation gives patients with infiltrative HCC an extra 3 months of life on...