The struggle to defeat Ebola virus disease continues globally, although it may not always make the headlines. To catch up on what you may have missed, here are some notable news items and journal articles published over the past few weeks that are worth a second look.
A study in Cell found that specific amino acid substitutions in the Ebola virus glycoprotein, while reducing tropism for bat cells, and such increased infectivity may have contributed to the wide geographic distribution of some viral lineages.
A recent case study of a West African Ebola survivor demonstrated theand detected Ebola-specific T cells, providing insights into lymphocyte specificity during the reconvalescent phase of Ebola virus disease.
The Ebola virus glycoprotein mutant GP-A82Vthe 2013-2016 West African epidemic, according to a recent study, and it was weakly associated with increased mortality during the epidemic.
A modeling study on a region of Sierra Leone provided numerical estimates for the effectiveness of ring vaccination to control future Ebola virus outbreaks. Investigators showed that, and more extensive vaccination and reinforcement of the health care system would increase the likelihood of containment even if the virus were more transmissible than in the past.
An RT-PCR (reverse transcriptase polymerase chain reaction) diagnostic assay using a glycoprotein target isin clinical samples than is an RT-PCR using a nucleoprotein target, according to a study in Diagnostic Microbiology & Infectious Disease.
Convalescent whole blood therapy is promising for treating Ebola virus disease in resource-poor settings,when resource mobilization is done, according to a study in the Journal of Infection.
Rapid chart reviews at Ebola virus disease survivor clinics should beand prioritize service delivery, according to a study in Sierra Leone.
The 2014-2016 outbreak of Ebola virus disease in West Africa, according to a study by the University of Nairobi.
Researchers have developed Microreact, a free,that has been used to monitor outbreaks of Ebola, Zika, and antibiotic-resistant microbes, according to a report in Microbial Genomics.
A study in the Journal of Virology found that Eboladuring the West African Ebola virus outbreak, impacting virus transmissibility and pathogenicity.
A literature review published in BMC Infectious Diseases foundfor Ebola and Marburg viruses to be lower than usually reported, with species differences despite high heterogeneity between studies.
A study of the scope and scale of thefound broad socioeconomic impacts, including reduced community cohesion, education loss, reduced child protection, widespread job losses, and food insecurity.