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Key clinical point: Increased cardiovascular (CV) risk, as assessed by the Systematic Coronary Risk Evaluation 2 system, was associated with a lower risk for prevalent and incident migraine, notably in women.

Major findings: Compared with individuals with the lowest CV risk scores (< 1%), those with CV risk scores of 1% to < 2.5% had a higher risk for prevalent migraine (odds ratio [OR], 0.93; 95% CI, 0.90-0.96) and incident migraine (OR, 0.63; 95% CI, 0.57-0.69), whereas individuals with CV risk scores ≥ 10% had a lower risk for prevalent migraine (OR, 0.43; 95% CI, 0.39-0.48) and incident migraine (OR, 0.17; 95% CI, 0.10-0.27). The association between migraine and CV risk was stronger in women than in men within the same CV risk categories.

Study details: This ~13-year prospective population-based study involved 140,915 adults (58.5% women), with 25,915 having prevalent migraine and 2224 having incident migraine.

Disclosure: The study was supported by the Dutch Research Council and others. Two authors reported receiving research grants, advisory board fees, or speaking fees from various sources.

Source: Al-Hassany L, MaassenVanDenBrink A, Kurth T. Cardiovascular risk scores and migraine status. JAMA Netw Open. Published online October 22, 2024. Source

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Key clinical point: Increased cardiovascular (CV) risk, as assessed by the Systematic Coronary Risk Evaluation 2 system, was associated with a lower risk for prevalent and incident migraine, notably in women.

Major findings: Compared with individuals with the lowest CV risk scores (< 1%), those with CV risk scores of 1% to < 2.5% had a higher risk for prevalent migraine (odds ratio [OR], 0.93; 95% CI, 0.90-0.96) and incident migraine (OR, 0.63; 95% CI, 0.57-0.69), whereas individuals with CV risk scores ≥ 10% had a lower risk for prevalent migraine (OR, 0.43; 95% CI, 0.39-0.48) and incident migraine (OR, 0.17; 95% CI, 0.10-0.27). The association between migraine and CV risk was stronger in women than in men within the same CV risk categories.

Study details: This ~13-year prospective population-based study involved 140,915 adults (58.5% women), with 25,915 having prevalent migraine and 2224 having incident migraine.

Disclosure: The study was supported by the Dutch Research Council and others. Two authors reported receiving research grants, advisory board fees, or speaking fees from various sources.

Source: Al-Hassany L, MaassenVanDenBrink A, Kurth T. Cardiovascular risk scores and migraine status. JAMA Netw Open. Published online October 22, 2024. Source

Key clinical point: Increased cardiovascular (CV) risk, as assessed by the Systematic Coronary Risk Evaluation 2 system, was associated with a lower risk for prevalent and incident migraine, notably in women.

Major findings: Compared with individuals with the lowest CV risk scores (< 1%), those with CV risk scores of 1% to < 2.5% had a higher risk for prevalent migraine (odds ratio [OR], 0.93; 95% CI, 0.90-0.96) and incident migraine (OR, 0.63; 95% CI, 0.57-0.69), whereas individuals with CV risk scores ≥ 10% had a lower risk for prevalent migraine (OR, 0.43; 95% CI, 0.39-0.48) and incident migraine (OR, 0.17; 95% CI, 0.10-0.27). The association between migraine and CV risk was stronger in women than in men within the same CV risk categories.

Study details: This ~13-year prospective population-based study involved 140,915 adults (58.5% women), with 25,915 having prevalent migraine and 2224 having incident migraine.

Disclosure: The study was supported by the Dutch Research Council and others. Two authors reported receiving research grants, advisory board fees, or speaking fees from various sources.

Source: Al-Hassany L, MaassenVanDenBrink A, Kurth T. Cardiovascular risk scores and migraine status. JAMA Netw Open. Published online October 22, 2024. Source

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