CME Supplements

Managing Bipolar Depression: An Evidence-Based Approach

This activity is jointly sponsored/co-provided by Global Medical Education, HealthmattersCME, and Postgraduate Institute for Medicine. This activity is supported by an independent educational grant from Sunovion Pharmaceuticals.


Bipolar disorder is characterized by the cyclical occurrence of elevated (manic or hypomanic) and depressed mood states. The illness, which includes the bipolar I and bipolar II subtypes, exacts a heavy toll in terms of quality of life, functioning, morbidity, comorbidity, and mortality.1 Depressive episodes and symptoms deserve particular attention: Not only do they dominate the long-term course of the illness; they are associated with similar or greater psychosocial impairment than corresponding levels of manic or hypomanic symptoms.1

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