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Mental health risks rise with age and stage for gender-incongruent youth

Key clinical point: Later stage puberty and older age were significantly associated with mental health problems in gender-incongruent adolescents.

Major finding: Significantly more gender-incongruent adolescents aged 15 years and older reported depression, self-harm, and suicidal thoughts, compared with those younger than 15 years (46% vs. 30%; 40% vs. 28%; and 36% vs. 23%, respectively).

Study details: The data come from a cross-sectional review of 300 gender-incongruent adolescents who were seen at a single center.

Disclosures: The study received no outside funding. Dr. Sorbara disclosed salary support from the Canadian Pediatric Endocrine Group fellowship program. Dr. de Vries had no financial conflicts to disclose. Dr. Cooper had no financial conflicts to disclose, and serves as a contributor to LGBTQ Youth Consult in Pediatric News.


Sorbara JC et al. Pediatrics. 2020 Sep 21. doi: 10.1542/peds.2019-3600; de Vries ALC et al. Pediatrics. 2020 Sep 21. doi: 10.1542/peds.2020-010611.