Depression
Evidence-Based Reviews
Therapy-resistant major depression When to consider ECT: Algorithm seeks respect for neglected therapy
Using ECT early—instead of as a last resort—is highly effective for ‘therapy-resistant’ depression.
From the Editor
ECT: Effective, but it has an image problem
Evidence-Based Reviews
Irritable bowel syndrome and psychiatric illness: Three clinical challenges
Target specific symptoms, consider possible drug-drug interactions, and watch for underlying life-threatening complications.
Evidence-Based Reviews
Therapy-resistant major depression The attraction of magnetism: How effective—and safe—is rTMS?
Despite early mixed results, magnetic stimulation of the prefrontal cortex is showing potential in major depression and other psychiatric...
Cases That Test Your Skills
The search for the hidden depressant
A teenager with longstanding ADHD and schizoaffective disorder lapses quickly into a deep depression with manic and suicidal features. Her doctors...
Evidence-Based Reviews
Atypical depression Puzzled? How to piece together symptoms and treatments
When do depressive symptoms become ‘atypical,’ and which antidepressants are most effective? Though evidence is incomplete, these authors...
Evidence-Based Reviews
Time to log off: New diagnostic criteria for problematic Internet use
The MOUSE screening tool helps identify five behaviors that spell too many hours online
Commentary
Shedding light on SAD therapy
Evidence-Based Reviews
Self-mutilation: Impulsive traits, high pain threshold suggest new drug therapies
Pathologic self-mutilation is easy to recognize but difficult to understand and treat. Here’s an in-depth look at this puzzling, sometimes...