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`Paradigm shift’: Luspatercept for MDS
In a first head-to-head comparison study, luspatercept for MDS significantly outperformed epoetin alfa in reducing transfusion dependence.
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Diabetes, cholesterol meds use drops after bariatric surgery
Undergoing bariatric surgery was associated with a substantial and long-lasting reduction in the use of lipid-lowering and antidiabetic...
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Immunotherapy plus chemo improves quality of life in NSCLC
The delays reported in time to definitive clinically meaningful deterioration “are particularly pertinent, given the anticipated continued...
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Liquid biopsy assay can predict CRC recurrence early
CRC has a relatively high recurrence rate even after curative-intent therapies.
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Weight loss linked to early death in older but healthy adults
“Clinicians should be aware that even minor weight loss of 5% or more in older adults without life-limiting illnesses can increase mortality risk...
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Breast conservation safe even with multiple-site tumors
“This is an important study confirming that breast conservation is feasible and safe for women with multiple ipsilateral breast cancers, with...
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Strong support for CBT as first-line treatment for insomnia in seniors
The American Academy of Sleep Medicine recommends CBT-I as first-line treatment for insomnia, with the key benefit being its exemplary safety...
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New data on IV ketamine for resistant depression in the elderly
Overall, 48% of participants achieved a response, and 24% achieved remission of depressive symptoms following the first 4 weeks of twice-weekly...
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Add-on antipsychotic beats switching meds in older adults with resistant depression
“These results are of great impact for clinicians managing older adults with treatment-resistant depression,” said Dr. Jennifer Gatchel.
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Antipsychotic cuts Alzheimer’s-related agitation
Brexpiprazole will become the first drug to be approved for agitation in AD, doctor speculates.
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Long-acting ART effective without viral suppression
“Instead of having the burden of taking a pill every day, patients with HIV can now have these choices of being able to forget about their...
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Doxy PEP does not lower risk of STIs in cisgender women
Women are known to be at higher risk of infection because the lining of the vagina is thinner than the skin of the penis, allowing for easier...
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Meningococcal vaccine shows benefit in STI prevention
“The duration of protective efficacy – a big thing in vaccines – is unknown. Still, this is really significant.”
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Eight-week TB treatment strategy shows potential
“Clinicians will not feel comfortable with the short regimens at this point, but it is remarkable that so many patients did well with shorter...
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Transplant vs. chemo: Similar AML survival rates
New study showed similar survival rates among AML patients treated solely with consolidation chemotherapy and those who received allogenic HCT.