News

High-dose chemo no better than standard dose for B-cell lymphoma
- Author:
- Mark S. Lesney, PhD
Conventional chemotherapy plus rituximab (R-CHOEP-14) was compared to high-dose chemotherapy plus rituximab...
News

New BTK inhibitor shows promise in previously failed B-cell malignancies
- Author:
- Mark S. Lesney, PhD
Pirtobrutinib (formerly known as LOXO-305) is an oral-dose, highly selective, reversible BTK inhibitor.
News

Prognostic gene signature identifies high- vs. low-risk DLBCL patients
- Author:
- Mark S. Lesney, PhD
The researchers calculated risk scores using their prognostic gene set in three additional published DLBCL studies.
News
CLL, MBL had lower response rates to flu vaccination, compared with healthy adults
- Author:
- Mark S. Lesney, PhD
Patients with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis were assessed for their immune response.
News
Immunoabsorption shows promise as an adjunct treatment for high-risk acquired hemophilia
- Author:
- Mark S. Lesney, PhD
Immunoabsorption therapy targeting factor VIII inhibitors appeared effective, but the researchers suggest that...
News
Ceftolozane-tazobactam found effective in critically ill patients with Pseudomonas aeruginosa infections
- Author:
- Mark S. Lesney, PhD
The primary outcome of the study was to assess the efficacy and toxicity of C/T therapy.
News
CDC: 20% of people in the U.S. are infected with an STD
- Author:
- Mark S. Lesney, PhD
STI incidence was determined using 2018 data and was highest in the 15- to 24 year-old age bracket.
News
First monthly injectable HIV treatment approved by FDA
- Author:
- Mark S. Lesney, PhD
Approval of Cabenuva was based upon two randomized, open-label, controlled clinical trials in 1,182 HIV-infected...
News
Global Ebola vaccine stockpile established
- Author:
- Mark S. Lesney, PhD
The stockpile, which is maintained in Switzerland, is designed to be readily deployed to other countries...
News

Allo-HSCT improves disease-free, but not overall survival in adults with ALL, compared with ped-inspired chemo
- Author:
- Mark S. Lesney, PhD
Allogeneic hematopoietic stem-cell transplantation improved disease-free survival, compared with Berlin-...
News

Eliminating hepatitis by 2030: HHS releases new strategic plan
- Author:
- Mark S. Lesney, PhD
The United States “is currently facing unprecedented hepatitis A outbreaks, while progress in preventing hepatitis B has stalled, and hepatitis C...
News

Eliminating hepatitis by 2030: HHS releases new strategic plan
- Author:
- Mark S. Lesney, PhD
The United States “is currently facing unprecedented hepatitis A outbreaks, while progress in preventing hepatitis B has stalled, and hepatitis C...
News
Mortality risks rise with age, infections, but not inhibitor status in persons with non-severe hemophilia A
- Author:
- Mark S. Lesney, PhD
Inhibitors occurred at an early age of 13 years with a prevalence of 2.6%, but were not associated with increased mortality.
News
Study shows no link between race and mortality in clear cell RCC
- Author:
- Mark S. Lesney, PhD
Older age and having regional or distant tumors were associated with an increased risk of death, while female...
News
‘Excellent short-term outcomes’ seen in HCV+ liver transplants to HCV– recipients
- Author:
- Mark S. Lesney, PhD
Liver transplantation using HCV-seropositive grafts to HCV-seronegative recipients resulted in “excellent short-...